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Sestrin Regulation of TORC1: Is Sestrin a Leucine Sensor?
Sestrins are highly conserved, stress-inducible proteins that inhibit target of rapamycin complex 1 (TORC1) signaling. Following their transcriptional induction, both vertebrate and invertebrate Sestrins turn on the AMP-activated protein kinase (AMPK) which activates the tuberous sclerosis complex (...
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| Publicado no: | Sci Signal |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4902175/ https://ncbi.nlm.nih.gov/pubmed/27273098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf2885 |
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