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Modular synthesis of the pyrimidine core of the manzacidins by divergent Tsuji–Trost coupling

The design, development and application of an efficient procedure for the concise synthesis of the 1,3-syn- and anti-tetrahydropyrimidine cores of manzacidins are reported. The intramolecular allylic substitution reaction of a readily available joint urea-type substrate enables the facile preparatio...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Bretzke, Sebastian, Scheeff, Stephan, Vollmeyer, Felicitas, Eberhagen, Friederike, Rominger, Frank, Menche, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902044/
https://ncbi.nlm.nih.gov/pubmed/27340499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.107
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