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Total syntheses of the archazolids: an emerging class of novel anticancer drugs

V-ATPase has recently emerged as a promising novel anticancer target based on extensive in vitro and in vivo studies with the archazolids, complex polyketide macrolides which present the most potent V-ATPase inhibitors known to date, rendering these macrolides important lead structures for the devel...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Scheeff, Stephan, Menche, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480361/
https://ncbi.nlm.nih.gov/pubmed/28684988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.108
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