Validating novel tau PET tracer [F-18]-AV-1451 (T807) on postmortem brain tissue

OBJECTIVE: To examine region and substrate-specific autoradiographic and in vitro binding patterns of PET tracer [F-18]-AV-1451 (previously known as T807), tailored to allow in vivo detection of paired helical filament tau-containing lesions, and to determine whether there is off-target binding to o...

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保存先:
書誌詳細
出版年:Ann Neurol
主要な著者: Marquie, Marta, Normandin, Marc D., Vanderburg, Charles R., Costantino, Isabel, Bien, Elizabeth A., Rycyna, Lisa G., Klunk, William E., Mathis, Chester A., Ikonomovic, Milos D., Debnath, Manik L., Vasdev, Neil, Dickerson, Bradford C., Gomperts, Stephen N., Growdon, John H., Johnson, Keith A., Frosch, Matthew P., Hyman, Bradley T., Gomez-Isla, Teresa
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900162/
https://ncbi.nlm.nih.gov/pubmed/26344059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24517
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