Validating novel tau PET tracer [F-18]-AV-1451 (T807) on postmortem brain tissue

OBJECTIVE: To examine region and substrate-specific autoradiographic and in vitro binding patterns of PET tracer [F-18]-AV-1451 (previously known as T807), tailored to allow in vivo detection of paired helical filament tau-containing lesions, and to determine whether there is off-target binding to o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ann Neurol
Prif Awduron: Marquie, Marta, Normandin, Marc D., Vanderburg, Charles R., Costantino, Isabel, Bien, Elizabeth A., Rycyna, Lisa G., Klunk, William E., Mathis, Chester A., Ikonomovic, Milos D., Debnath, Manik L., Vasdev, Neil, Dickerson, Bradford C., Gomperts, Stephen N., Growdon, John H., Johnson, Keith A., Frosch, Matthew P., Hyman, Bradley T., Gomez-Isla, Teresa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900162/
https://ncbi.nlm.nih.gov/pubmed/26344059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24517
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg