Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

Many hereditary and sporadic neurodegenerative disorders are characterized by the accumulation of aberrant proteins. In sporadic Parkinson's disease, representing the most prevalent movement disorder, oxidative and nitrosative stress are believed to contribute to disease pathogenesis, but the e...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Yao, Dongdong, Gu, Zezong, Nakamura, Tomohiro, Shi, Zhong-Qing, Ma, Yuliang, Gaston, Benjamin, Palmer, Lisa A., Rockenstein, Edward M., Zhang, Zhuohua, Masliah, Eliezer, Uehara, Takashi, Lipton, Stuart A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC490016/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15252205/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0404161101
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