Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

Many hereditary and sporadic neurodegenerative disorders are characterized by the accumulation of aberrant proteins. In sporadic Parkinson's disease, representing the most prevalent movement disorder, oxidative and nitrosative stress are believed to contribute to disease pathogenesis, but the e...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yao, Dongdong, Gu, Zezong, Nakamura, Tomohiro, Shi, Zhong-Qing, Ma, Yuliang, Gaston, Benjamin, Palmer, Lisa A., Rockenstein, Edward M., Zhang, Zhuohua, Masliah, Eliezer, Uehara, Takashi, Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC490016/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15252205/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0404161101
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