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Characterization of Plasmodium phosphatidylserine decarboxylase expressed in yeast and application for inhibitor screening

Phospholipid biosynthesis is critical for the development, differentiation and pathogenesis of several eukaryotic pathogens. Genetic studies have validated the pathway for phosphatidylethanolamine synthesis from phosphatidylserine catalyzed by phosphatidylserine decarboxylase enzymes (PSD) as a suit...

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Detalles Bibliográficos
Publicado en:Mol Microbiol
Autores principales: Choi, Jae-Yeon, Kumar, Vidya, Pachikara, Niseema, Garg, Aprajita, Lawres, Lauren, Toh, Justin Y., Voelker, Dennis R., Ben Mamoun, Choukri
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898484/
https://ncbi.nlm.nih.gov/pubmed/26585333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13280
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