Structure, Function and Inhibition of the Phosphoethanolamine Methyltransferases of the Human Malaria Parasites Plasmodium vivax and Plasmodium knowlesi

Phosphoethanolamine methyltransferases (PMTs) catalyze the three-step methylation of phosphoethanolamine to form phosphocholine, a critical step in the synthesis of phosphatidylcholine in a select number of eukaryotes including human malaria parasites, nematodes and plants. Genetic studies in the ma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Garg, Aprajita, Lukk, Tiit, Kumar, Vidya, Choi, Jae-Yeon, Augagneur, Yoann, Voelker, Dennis R., Nair, Satish, Mamoun, Choukri Ben
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357015/
https://ncbi.nlm.nih.gov/pubmed/25761669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09064
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