Identification of Gene Encoding Plasmodium knowlesi Phosphatidylserine Decarboxylase by Genetic Complementation in Yeast and Characterization of in Vitro Maturation of Encoded Enzyme

The 23-megabase genome of Plasmodium falciparum, the causative agent of severe human malaria, contains ∼5300 genes, most of unknown function or lacking homologs in other organisms. Identification of these gene functions will help in the discovery of novel targets for the development of antimalarial...

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Dettagli Bibliografici
Autori principali: Choi, Jae-Yeon, Augagneur, Yoann, Mamoun, Choukri Ben, Voelker, Dennis R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Lipids
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249073/
https://ncbi.nlm.nih.gov/pubmed/22057268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.313676
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