An improved and highly selective fluorescence assay for measuring phosphatidylserine decarboxylase activity

Phosphatidylserine decarboxylases (PSDs) catalyze the conversion of phosphatidylserine (PS) to phosphatidylethanolamine (PE), a critical step in membrane biogenesis and a potential target for development of antimicrobial and anti-cancer drugs. PSD activity has typically been quantified using radioac...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Choi, Jae-Yeon, Black, Raymond, Lee, HeeJung, Di Giovanni, James, Murphy, Robert C., Ben Mamoun, Choukri, Voelker, Dennis R.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2020
Subjects:
Methods and Resources
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335775/
https://ncbi.nlm.nih.gov/pubmed/32430397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013421
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