Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay

BACKGROUND: The phosphoethanolamine methyltransferase, PfPMT, of the human malaria parasite Plasmodium falciparum, a member of a newly identified family of phosphoethanolamine methyltransferases (PMT) found solely in some protozoa, nematodes, frogs, and plants, is involved in the synthesis of the ma...

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Main Authors: Bobenchik, April M, Choi, Jae-Yeon, Mishra, Arunima, Rujan, Iulian N, Hao, Bing, Voelker, Dennis R, Hoch, Jeffrey C, Mamoun, Choukri Ben
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824672/
https://ncbi.nlm.nih.gov/pubmed/20085640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-4
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