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Characterization of Plasmodium phosphatidylserine decarboxylase expressed in yeast and application for inhibitor screening

Phospholipid biosynthesis is critical for the development, differentiation and pathogenesis of several eukaryotic pathogens. Genetic studies have validated the pathway for phosphatidylethanolamine synthesis from phosphatidylserine catalyzed by phosphatidylserine decarboxylase enzymes (PSD) as a suit...

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Détails bibliographiques
Publié dans:Mol Microbiol
Auteurs principaux: Choi, Jae-Yeon, Kumar, Vidya, Pachikara, Niseema, Garg, Aprajita, Lawres, Lauren, Toh, Justin Y., Voelker, Dennis R., Ben Mamoun, Choukri
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898484/
https://ncbi.nlm.nih.gov/pubmed/26585333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13280
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