Characterization of Plasmodium phosphatidylserine decarboxylase expressed in yeast and application for inhibitor screening

Phospholipid biosynthesis is critical for the development, differentiation and pathogenesis of several eukaryotic pathogens. Genetic studies have validated the pathway for phosphatidylethanolamine synthesis from phosphatidylserine catalyzed by phosphatidylserine decarboxylase enzymes (PSD) as a suit...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Microbiol
Hauptverfasser: Choi, Jae-Yeon, Kumar, Vidya, Pachikara, Niseema, Garg, Aprajita, Lawres, Lauren, Toh, Justin Y., Voelker, Dennis R., Ben Mamoun, Choukri
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898484/
https://ncbi.nlm.nih.gov/pubmed/26585333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13280
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