Activation of the Renin-Angiotensin System Promotes Colitis Development

The renin-angiotensin system (RAS) plays pathogenic roles in renal and cardiovascular disorders, but whether it is involved in colitis is unclear. Here we show that RenTgMK mice that overexpress active renin from the liver developed more severe colitis than wild-type controls. More than 50% RenTgMK...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Shi, Yongyan, Liu, Tianjing, He, Lei, Dougherty, Urszula, Chen, Li, Adhikari, Sarbani, Alpert, Lindsay, Zhou, Guolin, Liu, Weicheng, Wang, Jiaolong, Deb, Dilip K., Hart, John, Liu, Shu Q., Kwon, John, Pekow, Joel, Rubin, David T., Zhao, Qun, Bissonnette, Marc, Li, Yan Chun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897651/
https://ncbi.nlm.nih.gov/pubmed/27271344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27552
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