Activation of the Renin-Angiotensin System Promotes Colitis Development

The renin-angiotensin system (RAS) plays pathogenic roles in renal and cardiovascular disorders, but whether it is involved in colitis is unclear. Here we show that RenTgMK mice that overexpress active renin from the liver developed more severe colitis than wild-type controls. More than 50% RenTgMK...

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保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Shi, Yongyan, Liu, Tianjing, He, Lei, Dougherty, Urszula, Chen, Li, Adhikari, Sarbani, Alpert, Lindsay, Zhou, Guolin, Liu, Weicheng, Wang, Jiaolong, Deb, Dilip K., Hart, John, Liu, Shu Q., Kwon, John, Pekow, Joel, Rubin, David T., Zhao, Qun, Bissonnette, Marc, Li, Yan Chun
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4897651/
https://ncbi.nlm.nih.gov/pubmed/27271344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27552
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