Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG

Development of a broad-spectrum synthetic vaccine against TB would represent an important advance to the limited vaccine armamentarium against TB. It is believed that the esx family of TB antigens may represent important vaccine candidates. However, only 4 esx antigens have been studied as potential...

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Dettagli Bibliografici
Pubblicato in:Hum Vaccin Immunother
Autori principali: Villarreal, Daniel O, Walters, Jewell, Laddy, Dominick J, Yan, Jian, Weiner, David B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896768/
https://ncbi.nlm.nih.gov/pubmed/25424922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.29574
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