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Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG

Development of a broad-spectrum synthetic vaccine against TB would represent an important advance to the limited vaccine armamentarium against TB. It is believed that the esx family of TB antigens may represent important vaccine candidates. However, only 4 esx antigens have been studied as potential...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Villarreal, Daniel O, Walters, Jewell, Laddy, Dominick J, Yan, Jian, Weiner, David B
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896768/
https://ncbi.nlm.nih.gov/pubmed/25424922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.29574
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