Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG

Development of a broad-spectrum synthetic vaccine against TB would represent an important advance to the limited vaccine armamentarium against TB. It is believed that the esx family of TB antigens may represent important vaccine candidates. However, only 4 esx antigens have been studied as potential...

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Bibliographic Details
Published in:Hum Vaccin Immunother
Main Authors: Villarreal, Daniel O, Walters, Jewell, Laddy, Dominick J, Yan, Jian, Weiner, David B
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2014
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896768/
https://ncbi.nlm.nih.gov/pubmed/25424922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.29574
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