Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG

Development of a broad-spectrum synthetic vaccine against TB would represent an important advance to the limited vaccine armamentarium against TB. It is believed that the esx family of TB antigens may represent important vaccine candidates. However, only 4 esx antigens have been studied as potential...

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Bibliografiska uppgifter
I publikationen:Hum Vaccin Immunother
Huvudupphovsmän: Villarreal, Daniel O, Walters, Jewell, Laddy, Dominick J, Yan, Jian, Weiner, David B
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2014
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896768/
https://ncbi.nlm.nih.gov/pubmed/25424922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.29574
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