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Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG

Development of a broad-spectrum synthetic vaccine against TB would represent an important advance to the limited vaccine armamentarium against TB. It is believed that the esx family of TB antigens may represent important vaccine candidates. However, only 4 esx antigens have been studied as potential...

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Bibliografski detalji
Izdano u:Hum Vaccin Immunother
Glavni autori: Villarreal, Daniel O, Walters, Jewell, Laddy, Dominick J, Yan, Jian, Weiner, David B
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896768/
https://ncbi.nlm.nih.gov/pubmed/25424922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.29574
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