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Structural characterization of the ternary complex that mediates termination of NF-κB signaling by IκBα
The transcription factor NF-κB is used in many systems for the transduction of extracellular signals into the expression of signal-responsive genes. Published structural data explain the activation of NF-κB through degradation of its dedicated inhibitor IκBα, but the mechanism by which NF-κB–mediate...
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出版年: | Proc Natl Acad Sci U S A |
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主要な著者: | , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
National Academy of Sciences
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4896678/ https://ncbi.nlm.nih.gov/pubmed/27185953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603488113 |
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