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Direct observation of a transient ternary complex during IκBα-mediated dissociation of NF-κB from DNA
We previously demonstrated that IκBα markedly increases the dissociation rate of DNA from NF-κB. The mechanism of this process remained a puzzle because no ternary complex was observed, and structures show that the DNA and IκBα binding sites on NF-κB are overlapping. The kinetics of interaction of I...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3890772/ https://ncbi.nlm.nih.gov/pubmed/24367071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318115111 |
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