Laddar...

Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier

Down syndrome (DS) is a significant risk factor for congenital heart disease (CHD), increasing the incidence 50 times over the general population. However, half of people with DS have a normal heart and thus trisomy 21 is not sufficient to cause CHD by itself. Ts65Dn mice are trisomic for orthologs...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Genetics
Huvudupphovsmän: Li, Huiqing, Edie, Sarah, Klinedinst, Donna, Jeong, Jun Seop, Blackshaw, Seth, Maslen, Cheryl L., Reeves, Roger H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Genetics Society of America 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896192/
https://ncbi.nlm.nih.gov/pubmed/27029737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.188045
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!