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Disome and trisome profiling reveal genome-wide targets of ribosome quality control

The ribosome-associated protein quality control (RQC) system that resolves stalled translation events is activated when ribosomes collide and form disome, trisome or higher order complexes. However, it is unclear whether this system distinguishes collision complexes formed on defective mRNAs from th...

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Vydáno v:Mol Cell
Hlavní autoři: Meydan, Sezen, Guydosh, Nicholas R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484464/
https://ncbi.nlm.nih.gov/pubmed/32615089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.06.010
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