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A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome
The hedgehog (HH) family of growth factors is involved in many aspects of growth and development, from the establishment of left-right axes at gastrulation to the patterning and formation of multiple structures in essentially every tissue and the maintenance and regulation of stem cell populations i...
Gardado en:
| Publicado en: | Prog Brain Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4405118/ https://ncbi.nlm.nih.gov/pubmed/22541295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-444-54299-1.00011-X |
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