A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog

Trisomy 21 results in phenotypes collectively referred to as Down syndrome (DS) including characteristic facial dysmorphology. Ts65Dn mice are trisomic for orthologs of about half of the genes found on human chromosome 21 and exhibit DS-like craniofacial abnormalities, including a small dysmorphic m...

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Hlavní autoři: Roper, Randall J., VanHorn, Justin F., Cain, Colyn C., Reeves, Roger H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820727/
https://ncbi.nlm.nih.gov/pubmed/19056491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2008.11.002
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