ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation

The t(8;21) translocation is one of the most frequent cytogenetic abnormalities in acute myeloid leukaemia (AML) and results in the RUNX1/RUNX1T1 rearrangement. Despite the causative role of the RUNX1/RUNX1T1 fusion gene in leukaemia initiation, additional genetic lesions are required for disease de...

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Publicado no:Nat Commun
Main Authors: Hartmann, Luise, Dutta, Sayantanee, Opatz, Sabrina, Vosberg, Sebastian, Reiter, Katrin, Leubolt, Georg, Metzeler, Klaus H., Herold, Tobias, Bamopoulos, Stefanos A., Bräundl, Kathrin, Zellmeier, Evelyn, Ksienzyk, Bianka, Konstandin, Nikola P., Schneider, Stephanie, Hopfner, Karl-Peter, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Middeke, Jan Moritz, Stölzel, Friedrich, Thiede, Christian, Wolf, Stephan, Bohlander, Stefan K., Preiss, Caroline, Chen-Wichmann, Linping, Wichmann, Christian, Sauerland, Maria Cristina, Büchner, Thomas, Berdel, Wolfgang E., Wörmann, Bernhard J., Braess, Jan, Hiddemann, Wolfgang, Spiekermann, Karsten, Greif, Philipp A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895769/
https://ncbi.nlm.nih.gov/pubmed/27252013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11733
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