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Thyroid hormone receptor-β1 signaling is critically involved in regulating secondary ossification via promoting transcription of the Ihh gene in the epiphysis

Thyroid hormone (TH) action is mediated through two nuclear TH receptors, THRα and THRβ. Although the role of THRα is well established in bone, less is known about the relevance of THRβ-mediated signaling in bone development. On ther basis of our recent finding that TH signaling is essential for ini...

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Détails bibliographiques
Publié dans:Am J Physiol Endocrinol Metab
Auteurs principaux: Xing, Weirong, Aghajanian, Patrick, Goodluck, Helen, Kesavan, Chandrasekhar, Cheng, Shaohong, Pourteymoor, Sheila, Watt, Heather, Alarcon, Catrina, Mohan, Subburaman
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895449/
https://ncbi.nlm.nih.gov/pubmed/27026086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00541.2015
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