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Conditional disruption of the osterix gene in chondrocytes during early postnatal growth impairs secondary ossification in the mouse tibial epiphysis

In our previous studies, we have found that the prepubertal increase in thyroid hormone levels induces osterix (Osx) signaling in hypertrophic chondrocytes to transdifferentiate them into osteoblasts. To test if Osx expressed in chondrocytes directly contributes to transdifferentiation and secondary...

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Detalles Bibliográficos
Publicado en:Bone Res
Main Authors: Xing, Weirong, Godwin, Catrina, Pourteymoor, Sheila, Mohan, Subburaman
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804621/
https://ncbi.nlm.nih.gov/pubmed/31646014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-019-0064-9
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