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Epiphyseal chondrocyte secondary ossification centers require thyroid hormone activation of Indian hedgehog and osterix signaling

Thyroid hormones (TH) are known to regulate endochondral ossification during skeletal development via acting directly in chondrocytes and osteoblasts. In this study, we focused on TH effects on the secondary ossification center (SOC), since the time of appearance of SOCs in several species coincides...

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Pubblicato in:J Bone Miner Res
Autori principali: Xing, Weirong, Cheng, Shaohong, Wergedal, Jon, Mohan, Subburaman
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487616/
https://ncbi.nlm.nih.gov/pubmed/24753031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2256
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