Thyroid hormone receptor-β1 signaling is critically involved in regulating secondary ossification via promoting transcription of the Ihh gene in the epiphysis

Thyroid hormone (TH) action is mediated through two nuclear TH receptors, THRα and THRβ. Although the role of THRα is well established in bone, less is known about the relevance of THRβ-mediated signaling in bone development. On ther basis of our recent finding that TH signaling is essential for ini...

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Pubblicato in:Am J Physiol Endocrinol Metab
Autori principali: Xing, Weirong, Aghajanian, Patrick, Goodluck, Helen, Kesavan, Chandrasekhar, Cheng, Shaohong, Pourteymoor, Sheila, Watt, Heather, Alarcon, Catrina, Mohan, Subburaman
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895449/
https://ncbi.nlm.nih.gov/pubmed/27026086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00541.2015
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