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USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2
Histone deacetylases (HDACs) are major epigenetic modulators involved in a broad spectrum of human diseases including cancers. As HDACs are promising targets of cancer therapy, it is important to understand the mechanisms of HDAC regulation. In this study, we show that ubiquitin-specific peptidase 4...
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| Gepubliceerd in: | Oncogene |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4895393/ https://ncbi.nlm.nih.gov/pubmed/26411366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.349 |
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