NKAP regulates iNKT cell proliferation and differentiation into ROR-γt expressing NKT17 cells

Invariant Natural Killer T (iNKT) cells are a unique lineage with characteristics of both adaptive and innate lymphocytes, and recognize glycolipid presented by an MHC Class I-like CD1d molecule. During thymic development, iNKT cells also differentiate into NKT1, NKT2 and NKT17 functional subsets th...

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Veröffentlicht in:J Immunol
Hauptverfasser: Thapa, Puspa, Chen, Meibo W., McWilliams, Douglas C., Belmonte, Paul, Constans, Megan, Sant’Angelo, Derek B., Shapiro, Virginia Smith
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893932/
https://ncbi.nlm.nih.gov/pubmed/27183586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501653
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