EGFR fusions as novel therapeutic targets in lung cancer

Here, we report that novel epidermal growth factor receptor (EGFR) gene fusions comprising the N-terminal of EGFR linked to various fusion partners, most commonly RAD51, are recurrent in lung cancer. We describe five patients with metastatic lung cancer whose tumors harbored EGFR fusions, four of wh...

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書誌詳細
出版年:Cancer Discov
主要な著者: Konduri, Kartik, Gallant, Jean-Nicolas, Chae, Young Kwang, Giles, Francis J., Gitlitz, Barbara J., Gowen, Kyle, Ichihara, Eiki, Owonikoko, Taofeek K., Peddareddigari, Vijay, Ramalingam, Suresh S., Reddy, Satyanarayan K., Eaby-Sandy, Beth, Vavalà, Tiziana, Whiteley, Andrew, Chen, Heidi, Yan, Yingjun, Sheehan, Jonathan H., Meiler, Jens, Morosini, Deborah, Ross, Jeffrey S., Stephens, Philip J., Miller, Vincent A., Ali, Siraj M., Lovly, Christine M.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893907/
https://ncbi.nlm.nih.gov/pubmed/27102076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0075
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