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Shades of T790M – intratumor heterogeneity in EGFR mutant lung cancer
In the setting of recent exciting clinical results and numerous on-going trials, Piotrowska and colleagues explore mechanisms of acquired resistance to the mutant specific EGFR inhibitor, rociletinib, and demonstrate that loss of T790M, EGFR amplification, and small cell transformation are all clini...
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| Gepubliceerd in: | Cancer Discov |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499857/ https://ncbi.nlm.nih.gov/pubmed/26152920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0616 |
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