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Ca(2+) is a key factor in α-synuclein-induced neurotoxicity
Aggregation of α-synuclein leads to the formation of oligomeric intermediates that can interact with membranes to form pores. However, it is unknown how this leads to cell toxicity in Parkinson's disease. We investigated the species-specific effects of α-synuclein on Ca(2+) signalling in primar...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Cell Sci |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Company of Biologists Ltd
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4893653/ https://ncbi.nlm.nih.gov/pubmed/26989132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.180737 |
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