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Lipid peroxidation is essential for α‐synuclein‐induced cell death

Parkinson's disease is the second most common neurodegenerative disease and its pathogenesis is closely associated with oxidative stress. Deposition of aggregated α‐synuclein (α‐Syn) occurs in familial and sporadic forms of Parkinson's disease. Here, we studied the effect of oligomeric α‐S...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Angelova, Plamena R., Horrocks, Mathew H., Klenerman, David, Gandhi, Sonia, Abramov, Andrey Y., Shchepinov, Mikhail S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471127/
https://ncbi.nlm.nih.gov/pubmed/25580849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13024
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