The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1

Cytoplasmic dynein, the major motor driving retrograde axonal transport, must be actively localized to axon terminals. This localization is critical as dynein powers essential retrograde trafficking events required for neuronal survival, such as neurotrophic signaling. Here, we demonstrate that the...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Twelvetrees, Alison E., Pernigo, Stefano, Sanger, Anneri, Guedes-Dias, Pedro, Schiavo, Giampietro, Steiner, Roberto A., Dodding, Mark P., Holzbaur, Erika L.F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893161/
https://ncbi.nlm.nih.gov/pubmed/27210554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.04.046
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