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JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors

Regulation of the opposing kinesin and dynein motors that drive axonal transport is essential to maintain neuronal homeostasis. Here, we examine coordination of motor activity by the scaffolding protein JNK-interacting protein 1 (JIP1), which we find is required for long-range anterograde and retrog...

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Detalhes bibliográficos
Main Authors: Fu, Meng-meng, Holzbaur, Erika L.F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734084/
https://ncbi.nlm.nih.gov/pubmed/23897889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201302078
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