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JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors
Regulation of the opposing kinesin and dynein motors that drive axonal transport is essential to maintain neuronal homeostasis. Here, we examine coordination of motor activity by the scaffolding protein JNK-interacting protein 1 (JIP1), which we find is required for long-range anterograde and retrog...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3734084/ https://ncbi.nlm.nih.gov/pubmed/23897889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201302078 |
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