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Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

Dynein and kinesin motor proteins transport cellular cargos toward opposite ends of microtubule tracks. In neurons, microtubules are abundantly decorated with microtubule-associated proteins (MAPs) such as tau. Motor proteins thus encounter MAPs frequently along their path. To determine the effects...

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Detalhes bibliográficos
Main Authors: Dixit, Ram, Ross, Jennifer L., Goldman, Yale E., Holzbaur, Erika L. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866193/
https://ncbi.nlm.nih.gov/pubmed/18202255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1152993
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