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Tau directs intracellular trafficking by regulating the forces exerted by kinesin and dynein teams

Organelles, proteins, and mRNA are transported bidirectionally along microtubules by plus-end directed kinesin and minus-end directed dynein motors. Microtubules are decorated by microtubule-associated proteins (MAPs) that organize the cytoskeleton, regulate microtubule dynamics and modulate the int...

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Vydáno v:Traffic
Hlavní autoři: Chaudhary, Abdullah R., Berger, Florian, Berger, Christopher L., Hendricks, Adam G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783771/
https://ncbi.nlm.nih.gov/pubmed/29077261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12537
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