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In vivo optical trapping indicates kinesin’s stall force is reduced by dynein during intracellular transport
Kinesin and dynein are fundamental components of intracellular transport, but their interactions when simultaneously present on cargos are unknown. We built an optical trap that can be calibrated in vivo during data acquisition for each individual cargo to measure forces in living cells. Comparing d...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587256/ https://ncbi.nlm.nih.gov/pubmed/23404705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219961110 |
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