Motor Domain Phosphorylation Modulates Kinesin-1 Transport

Disruptions in microtubule motor transport are associated with a variety of neurodegenerative diseases. Post-translational modification of the cargo-binding domain of the light and heavy chains of kinesin has been shown to regulate transport, but less is known about how modifications of the motor do...

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Bibliografski detalji
Glavni autori: DeBerg, Hannah A., Blehm, Benjamin H., Sheung, Janet, Thompson, Andrew R., Bookwalter, Carol S., Torabi, Seyed F., Schroer, Trina A., Berger, Christopher L., Lu, Yi, Trybus, Kathleen M., Selvin, Paul R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Molecular Biophysics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820893/
https://ncbi.nlm.nih.gov/pubmed/24072715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515510
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