Motor Domain Phosphorylation Modulates Kinesin-1 Transport

Disruptions in microtubule motor transport are associated with a variety of neurodegenerative diseases. Post-translational modification of the cargo-binding domain of the light and heavy chains of kinesin has been shown to regulate transport, but less is known about how modifications of the motor do...

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Detalhes bibliográficos
Main Authors: DeBerg, Hannah A., Blehm, Benjamin H., Sheung, Janet, Thompson, Andrew R., Bookwalter, Carol S., Torabi, Seyed F., Schroer, Trina A., Berger, Christopher L., Lu, Yi, Trybus, Kathleen M., Selvin, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820893/
https://ncbi.nlm.nih.gov/pubmed/24072715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515510
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