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In vivo optical trapping indicates kinesin’s stall force is reduced by dynein during intracellular transport

Kinesin and dynein are fundamental components of intracellular transport, but their interactions when simultaneously present on cargos are unknown. We built an optical trap that can be calibrated in vivo during data acquisition for each individual cargo to measure forces in living cells. Comparing d...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Blehm, Benjamin H., Schroer, Trina A., Trybus, Kathleen M., Chemla, Yann R., Selvin, Paul R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587256/
https://ncbi.nlm.nih.gov/pubmed/23404705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219961110
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