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The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1

Cytoplasmic dynein, the major motor driving retrograde axonal transport, must be actively localized to axon terminals. This localization is critical as dynein powers essential retrograde trafficking events required for neuronal survival, such as neurotrophic signaling. Here, we demonstrate that the...

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Publicat a:Neuron
Autors principals: Twelvetrees, Alison E., Pernigo, Stefano, Sanger, Anneri, Guedes-Dias, Pedro, Schiavo, Giampietro, Steiner, Roberto A., Dodding, Mark P., Holzbaur, Erika L.F.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893161/
https://ncbi.nlm.nih.gov/pubmed/27210554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.04.046
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