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SKIP controls lysosome positioning using a composite kinesin-1 heavy and light chain-binding domain

The molecular interplay between cargo recognition and regulation of the activity of the kinesin-1 microtubule motor is not well understood. Using the lysosome adaptor SKIP (also known as PLEKHM2) as model cargo, we show that the kinesin heavy chains (KHCs), in addition to the kinesin light chains (K...

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Detaylı Bibliyografya
Yayımlandı:J Cell Sci
Asıl Yazarlar: Sanger, Anneri, Yip, Yan Y., Randall, Thomas S., Pernigo, Stefano, Steiner, Roberto A., Dodding, Mark P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Ltd 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450233/
https://ncbi.nlm.nih.gov/pubmed/28302907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.198267
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