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SKIP controls lysosome positioning using a composite kinesin-1 heavy and light chain-binding domain
The molecular interplay between cargo recognition and regulation of the activity of the kinesin-1 microtubule motor is not well understood. Using the lysosome adaptor SKIP (also known as PLEKHM2) as model cargo, we show that the kinesin heavy chains (KHCs), in addition to the kinesin light chains (K...
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| Publicado no: | J Cell Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5450233/ https://ncbi.nlm.nih.gov/pubmed/28302907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.198267 |
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