Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease

The underlying relation between Parkinson’s disease (PD) etiopathology and its major risk factor, aging, is largely unknown. In light of the causative link between genome stability and aging, we investigate a possible nexus between DNA damage accumulation, aging, and PD by assessing aging-related DN...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Sepe, Sara, Milanese, Chiara, Gabriels, Sylvia, Derks, Kasper W.J., Payan-Gomez, Cesar, van IJcken, Wilfred F.J., Rijksen, Yvonne M.A., Nigg, Alex L., Moreno, Sandra, Cerri, Silvia, Blandini, Fabio, Hoeijmakers, Jan H.J., Mastroberardino, Pier G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2016
Ämnen:
Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893155/
https://ncbi.nlm.nih.gov/pubmed/27210754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.071
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