Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease

The underlying relation between Parkinson’s disease (PD) etiopathology and its major risk factor, aging, is largely unknown. In light of the causative link between genome stability and aging, we investigate a possible nexus between DNA damage accumulation, aging, and PD by assessing aging-related DN...

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Pubblicato in:Cell Rep
Autori principali: Sepe, Sara, Milanese, Chiara, Gabriels, Sylvia, Derks, Kasper W.J., Payan-Gomez, Cesar, van IJcken, Wilfred F.J., Rijksen, Yvonne M.A., Nigg, Alex L., Moreno, Sandra, Cerri, Silvia, Blandini, Fabio, Hoeijmakers, Jan H.J., Mastroberardino, Pier G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2016
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Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893155/
https://ncbi.nlm.nih.gov/pubmed/27210754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.071
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