Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease

The underlying relation between Parkinson’s disease (PD) etiopathology and its major risk factor, aging, is largely unknown. In light of the causative link between genome stability and aging, we investigate a possible nexus between DNA damage accumulation, aging, and PD by assessing aging-related DN...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Sepe, Sara, Milanese, Chiara, Gabriels, Sylvia, Derks, Kasper W.J., Payan-Gomez, Cesar, van IJcken, Wilfred F.J., Rijksen, Yvonne M.A., Nigg, Alex L., Moreno, Sandra, Cerri, Silvia, Blandini, Fabio, Hoeijmakers, Jan H.J., Mastroberardino, Pier G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893155/
https://ncbi.nlm.nih.gov/pubmed/27210754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.071
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