Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease

The underlying relation between Parkinson’s disease (PD) etiopathology and its major risk factor, aging, is largely unknown. In light of the causative link between genome stability and aging, we investigate a possible nexus between DNA damage accumulation, aging, and PD by assessing aging-related DN...

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Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Sepe, Sara, Milanese, Chiara, Gabriels, Sylvia, Derks, Kasper W.J., Payan-Gomez, Cesar, van IJcken, Wilfred F.J., Rijksen, Yvonne M.A., Nigg, Alex L., Moreno, Sandra, Cerri, Silvia, Blandini, Fabio, Hoeijmakers, Jan H.J., Mastroberardino, Pier G.
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2016
Teme:
Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893155/
https://ncbi.nlm.nih.gov/pubmed/27210754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.071
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