Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson’s disease

The involvement of DNA damage and repair in aging processes is well established. Aging is an unequivocal risk factor for chronic neurodegenerative diseases, underscoring the relevance of investigations into the role that DNA alterations may have in the pathogenesis of these diseases. Consistently, e...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Milanese, Chiara, Cerri, Silvia, Ulusoy, Ayse, Gornati, Simona V., Plat, Audrey, Gabriels, Sylvia, Blandini, Fabio, Di Monte, Donato A., Hoeijmakers, Jan H., Mastroberardino, Pier G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062587/
https://ncbi.nlm.nih.gov/pubmed/30050065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0848-7
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